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Occurs suddenly on only one side
Amlodipine medication guide
Do not assume every swollen ankle is caused by amlodipine, because heart, kidney, vascular, and other conditions can cause similar symptoms.
2. Severe Dizziness or Fainting
Amlodipine lowers blood pressure.
If blood pressure falls too much, you may experience:
Lightheadedness
Weakness
Blurred vision
Feeling faint
Actual fainting
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This can be more noticeable when standing up quickly.
Persistent or severe dizziness deserves evaluation, especially if it begins after a dose increase or medication change.
3. A Very Fast or Pounding Heartbeat
Some people notice palpitations or a racing heartbeat after starting amlodipine.
This may feel like:
Fluttering
Pounding
Skipped beats
A fast pulse
Occasional mild palpitations can happen, but repeated or severe episodes should be discussed with a healthcare professional.
Seek urgent care if they occur with chest pain, fainting, or severe shortness of breath.
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4. New or Worsening Chest
Amlodipine is actually used to help treat certain types of angina, but rarely, chest pain can worsen when treatment begins or the dose changes, especially in people with severe coronary artery disease.
New, severe, or worsening chest pain should always be taken seriously.
Call emergency services if chest discomfort is:
Heavy
Crushing
Persistent
Spreading to the arm, jaw, back, or shoulder
Accompanied by sweating, nausea, or shortness of breath
5. Shortness of Breath
Breathlessness is not one of the most common amlodipine side effects, but it can be important when it appears with swelling, chest discomfort, or marked weakness.
Possible causes include:
Excess fluid retention
Heart problems
Lung problems
An allergic reaction
Another unrelated condition
Sudden or severe shortness of breath needs prompt medical evaluation.
6. Severe Fatigue or Weakness
Amlodipine is actually used to help treat certain types of angina, but rarely, chest pain can worsen when treatment begins or the dose changes, especially in people with severe coronary artery disease.